S3 E08: Your Mind the Gut Microbiome
with Dr. Aya Osman
Listen now
Are we really what we eat? Research on the gut microbiome suggests we really are! This week we speak to Dr. Aya Osman who researches how the gut microbiome influences our brain and behaviour. Dr Osman explains the role of the gut microbiome in addiction and autism and how we can study these connections. We learn what foods are best for a healthy gut. Ava and Beth discuss their personal experiences with the gut microbiome with some pretty rogue stories!
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Dr. Aya Osman
Research discussed
Find Dr. Osman on Twitter
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Research by Dr. Osman​
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Osman, A., Mervosh, N. L., Strat, A. N., Euston, T. J., Zipursky, G., Pollak, R. M., ... & Kiraly, D. D. (2023). Acetate supplementation rescues social deficits and alters transcriptional regulation in prefrontal cortex of Shank3 deficient mice. Brain, Behavior, and Immunity, 114, 311-324
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Lucerne, K. E., Osman, A., Meckel, K. R., & Kiraly, D. D. (2021). Contributions of neuroimmune and gut-brain signaling to vulnerability of developing substance use disorders. Neuropharmacology, 192, 108598..
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Osman, A., Hofford, R. S., Meckel, K. R., Dave, Y. A., Zeldin, S. M., Shipman, A. L., ... & Kiraly, D. D. (2023). Dietary polyphenols drive dose-dependent behavioral and molecular alterations to repeated morphine. Scientific Reports, 13(1), 12223.
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Other research discussed
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Bercik, P., Denou, E., Collins, J., Jackson, W., Lu, J., Jury, J., ... & Collins, S. M. (2011). The intestinal microbiota affect central levels of brain-derived neurotropic factor and behavior in mice. Gastroenterology, 141(2), 599-609.
Infographics from Dr. Osman
